منابع مشابه
Anti - Phosphocholine Hybridoma Antibodies
Three major groups of antibodies have been identified during the analysis of the clonal response to phosphoeholine (PC). t The predominant one shows multiple molecular features of the PC-binding myeloma protein (PC-BMP) TEPC 15 (1-3), and two others possess idiotypes (Id) and L-chain characteristics of two other PCBMP, M511 (2, 4) and M603 (5). All three Id groups are conserved in inbred mice (...
متن کامل354 Anti - Phosphocholine Hybridoma Antibodies
Three major groups of antibodies have been identified during the analysis of the clonal response to phosphoeholine (PC). t The predominant one shows multiple molecular features of the PC-binding myeloma protein (PC-BMP) TEPC 15 (1-3), and two others possess idiotypes (Id) and L-chain characteristics of two other PCBMP, M511 (2, 4) and M603 (5). All three Id groups are conserved in inbred mice (...
متن کاملBispecific Antibodies from Hybrid Hybridoma
Hybrid hybridomas (also termed quadromas or tetradomas) are man-made cell lines that secrete bispecific antibodies (bsAb) with two different specificities being able to crosslink two distinct molecules. Such antibodies do not occur in nature and have been originally developed to improve immunohistochemical staining procedures and immunoassays (Milstein and Cuello 1983; Suresh et al. 1986). Inte...
متن کاملHybridoma Technique in Pharmaceutical Science
Hybridomas are the specific cells that have specific character to produce desire antibody. To produce monoclonal antibodies, β cells are removed from the spleen of an animal that has been immunized with the releant antigen. These β cells are then fused with myeloma tumor cells in the presence of PEG. The use of HGPRT cells assured that only hybridomas are selected. The fused hybrid cells (hybri...
متن کامل1380 Inducible Hybridoma Suppressor Cells
During the past several years, our laboratory has studied the mechanism of immune suppression in the 4-hydroxy-3-nitrophenyl acetyl (NP) 1 system. In this model system, both cell-mediated and humoral immunity (1-3) have been analyzed. The findings have permitted integration of the data into a single linear scheme of cellular interactions (3-5). Based on the results obtained in our and other lab...
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ژورنال
عنوان ژورنال: The Journal of Japan Atherosclerosis Society
سال: 1983
ISSN: 0386-2682,2185-8284
DOI: 10.5551/jat1973.11.2_449